Selective laser trabeculoplasty (SLT) is an advanced, non-invasive primary or secondary treatment of increased intraocular pressure. It employs short pulses of specific wavelength that selectively target the melanin-containing cells in the trabecular meshwork while preserving the adjacent non-pigmented eye structures. Low-energy laser irradiation evokes cytokines response what consequently activates the macrophages which clear the damaged cells. Increased trabecular meshwork porosity restores balanced aqueous outflow and lowers the intraocular pressure.